Allele-Specific Quantification of Structural Variations in Cancer Genomes
نویسندگان
چکیده
منابع مشابه
Allele-Specific Quantification of Structural Variations in Cancer Genomes
Aneuploidy and structural variations (SVs) generate cancer genomes containing a mixture of rearranged genomic segments with extensive somatic copy number alterations. However, existing methods can identify either SVs or allele-specific copy number alterations but not both simultaneously, which provides a limited view of cancer genome structure. Here, we introduce Weaver, an algorithm for the qu...
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ژورنال
عنوان ژورنال: Cell Systems
سال: 2016
ISSN: 2405-4712
DOI: 10.1016/j.cels.2016.05.007